UNCG researchers are looking for people who:
Physical Activity and Alzheimer’s Disease - 2 (PAAD-2) is designed to test the effects of a 1-year virtual exercise program on the cognitive performance of adults relative to their risk for Alzheimer’s disease.
Results from this study may help researchers to understand the benefits of physical activity for persons with a family history of Alzheimer’s disease (AD) relative to a person's genetic risk for AD.
Participants will be asked to complete up to 6 in-person data collection visits over 12-16 months. During data collection visits, participants will answer questions about their health, perform cognitive tests, and complete an aerobic fitness test.
Participants will also be asked to provide a blood sample and a saliva sample for APOE genotyping. If a participant can safely complete an MRI scan, they will be asked to do so.
After completing pre-testing, participants will be randomly assigned to either a 12-month virtual exercise program (exercise group) or asked to maintain their current level of physical activity for 12 months (control group). The control group will receive a free short-term membership to their local YMCA (or cash equivalent) upon study completion.
All participants will be compensated for data collection visits.